NEW!
Histamine intolerance (HI) is a complex but treatable condition. With the right diet, supplements, and lifestyle changes tailored to the individual, most people can see a big improvement in their symptoms.
$250.00
Histamine & Histamine Intolerance
Histamine is a bioactive molecule that functions as an important neurotransmitter and inflammatory mediator.
Histamine intolerance occurs when there is an imbalance between histamine accumulation and the body’s ability to break it down.
Causes of Histamine Intolerance
Histamine intolerance is mainly caused by low levels of an enzyme called DAO. This enzyme helps break down histamine in the digestive system. When there isn’t enough DAO, histamine builds up and causes symptoms.
Some individuals inherit genetic variations that reduce their ability to produce adequate amounts of DAO enzyme or affect how efficiently the enzyme functions.
Conditions such as SIBO (small intestinal bacterial overgrowth), IBS (irritable bowel syndrome), IBD (inflammatory bowel disease), celiac disease, and gut permeability (leaky gut) can damage intestinal cells that produce DAO enzymes, leading to excess histamine.
Certain drugs including some antibiotics, anti-depressants, and pain relievers can block DAO activity or release histamine from cells.
Consuming excessive amounts of histamine-rich foods can overwhelm even normal DAO levels, temporarily creating intolerance symptoms.
Genetic testing of DAO variations offers a more reliable diagnostic pathway for histamine intolerance. Other approaches may only provide a momentary snapshot, genetic analysis offers a reliable biomarker for histamine intolerance.
Histamine intolerance can be challenging to identify because symptoms mimic allergies and other food sensitivities.
Traditional methods of assessment include symptom history, dietary trials, and blood testing for enzyme levels, but these approaches often lack precision.
PreviMedica’s Genetic Histamine Intolerance test provides a more personalized approach by analyzing genetic variants in the DAO (AOC1) gene, which plays a critical role in breaking down histamine in the gut.
Genetic variations in DAO genes provide stable, unchanging diagnostic markers throughout a person’s life.
The DAO (Diamine Oxidase) encoding gene, also known as AOC1, is responsible for breaking down histamine in the digestive tract before it enters circulation. This enzyme plays a crucial role in preventing histamine overload from dietary sources.
Genetic testing reveals the underlying mechanism instead of just measuring symptoms.
Specific genetic variants can guide more targeted therapeutic approaches and supplement dosing.
This HI test assesses genetic variants in the DAO (AOC1) gene and combines them with a symptom score to determine the likelihood of histamine intolerance.
Score 1: Genetic Risk Score – Based on the presence of specific DAO gene variants that may reduce enzyme function.
Score 2: Symptom Risk Score – To be filled out by the practitioner and/or patient, based on the reported symptoms associated with histamine intolerance.
Combined Score: Both scores are then combined assess risk and to guide dietary and lifestyle adjustments for those with Genetic Histamine Intolerance.
$250
Managing histamine intolerance typically requires a multi-faceted approach combining dietary changes with strategic supplementation and medications when necessary.
Treatment should be personalized and supervised by healthcare providers knowledgeable about histamine intolerance, as supplement quality and appropriate dosing can significantly impact results.
Supplemental diamine oxidase can be taken before meals containing histamine to enhance the body’s ability to break down dietary histamine. These supplements are available in various strengths and formulations.
Specific probiotic strains can help reduce histamine production in the gut and restore healthy intestinal barrier function, particularly strains like Bifidobacterium longum and lactobacillus plantarum.
$250
Functional Laboratory Testing aimed at personalized nutrition and prevention
Functional testing can meet your unique needs and particularly the Alcat Test and Cellular Nutrition Assays determine how your immune cells react to various exposures.
The Alcat food and chemical sensitivity test identifies adverse reactions to foods and other dietary items, chemicals, medicinal herbs, functional foods and many other substances. As such it provides a foundation for personalized eating. It tests how your innate immune cells react to various exposures and is a reliable method tto determine which foods and other substances should be restricted.
Other immune cells can also be used as a biomarker for the absorption and metabolism of nutrients. The Cellular Nutrition Assays (CNA) show which nutrients, botanicals, antioxidants etc. are insufficient and which are beneficial for an individual. In this test we actually feed the cells different nutrients one by one to see which ones improve their function. In the Antioxidant Protection Assay we look at which specific antioxidants protect the cells when they are placed under stress.
The functional nutrition tests can be complimented using indicators or risk assessment for disease processes: for example, CICA for intestinal complaints or the telomere length test to determine the ratio between actual age and the so-called biological age.
Cell Science Systems (CSS) was the clear winner of the prestigious Frost & Sullivan Award, which was granted only once in 2016.
These points were particularly highlighted:
We are here to support you at every step. Receive your test test kit and have your blood drawn at a lab or in the convenience of your home or office.
Ready? Your PreviMedica nutrition expert provides individualized guidance based on your test results and needs. Get customized supplements with the Previ Expert package.
Your are unique. With PreviMedica’s functional lab tests and nutrition guidance you will know which foods and supplements are good for you and your body will love it!
You can expect your test kit to arrive in 3-5 business days, depending on where you reside.
You can order directly through our website or call PreviMedica for a consultation and one of our doctors will order the test for you. There is no additional charge. We do require a blood draw to be provided by a medical professional that we can assist in arranging. You may also take part in our additional support programs.
No. Fasting is not required. However, we recommend NOT taking any medications or supplements at least 4 hours prior to the blood draw.
You will be notified via email when your specimen arrives at the laboratory with notification of when to expect your results. Once your results are ready, they will be uploaded to our secure portal and you will receive an email notification indicating your results are ready for you to view. Please follow the instructions to start your account on the PreviMedica portal.
With every test offered by PreviMedica, you will be eligible to receive a complimentary 30-minute phone or video consultation with a member of our support team to discuss test results.
To request an appointment for a complimentary session, please complete this form: https://cellsciencesystems.com/resultsreview
The genetic component of the DAO enzyme is not necessary to test more than once.
